CD86 Antibody

• Gene Name:

  CD86 molecule

• Gene Aliases:

  Activation B7-2 antigen; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28LG2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) ; CTLA-4 counter-receptor B7.2; FUN-1; LAB72; T-lymphocyte activation antigen CD86.

• Gene ID:

  942

• Accession Number:

  NP_001193853.1NP_001193854.1NP_008820.3NP_787058.4NP_795711.1

• Reactivity:

  Human

• Immunogen:

  B-lymphoblastoid cell line ARH 77

• Target:

  Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

• Clonality:

  Monoclonal

• Clone:

  BU63

• Conjugation:

  FITC

• Type:

  Monoclonal Antibody

• Applications:

  Flow cytometry

• Purification:

  Purified by size-exclusion chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  20 ul / test

• Format:

  Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• Buffer:

  The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

• Reconstitution:

  2°C to 8°C

• Fragment:

  IgG1

• Specificity:

  HLDA V; WS Code BP BP072 HLDA V; WS Code A A109 HLDA VI; WS Code BP 95 HLDA VI; WS Code B CD86.9//

• NCBI Gene Symbol:

  CD86

• Host or Source:

  Mouse

• Protein Name:

  T-lymphocyte activation antigen CD86

• Gene Name URL:

  CD86

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001206924.1NM_001206925.1NM_006889.4NM_175862.4NM_176892.1