CD80 Antibody

• Gene Name :

  CD80 molecule

• Gene Aliases :

  Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) ; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80.

• Gene ID :

  941

• Accession Number :

  NP_005182.1

• Reactivity :

  Human

• Immunogen :

  Extracellular domain of human CD80 fused to human IgG1 (Fc)

• Target :

  Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.

• Clonality :

  Monoclonal

• Clone :

  MEM-233

• Conjugation :

  APC

• Type :

  Monoclonal Antibody

• Applications :

  Flow cytometry

• Purification :

  Purified by size-exclusion chromatography

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  10 ul / test

• Format :

  Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• Buffer :

  The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

• Reconstitution :

  2°C to 8°C

• Fragment :

  IgG1

• Specificity :

  The antibody MEM-233 reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.

• NCBI Gene Symbol :

  CD80

• Host or Source :

  Mouse

• Protein Name :

  T-lymphocyte activation antigen CD80

• Gene Name URL :

  CD80

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_005191.3