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CD79A Antibody

CAT: 0247-OAEE00968-100TSize: 100 TestsDry Ice: NoHazardous: No
CAT#:0247-OAEE00968-100TSize:100 Tests
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
CD79a molecule
Gene Aliases
B-cell antigen receptor complex-associated protein alpha chain; CD79a antigen (immunoglobulin-associated alpha) ; CD79a molecule, immunoglobulin-associated alpha; IGA; ig-alpha; MB-1; MB-1 membrane glycoprotein; membrane-bound immunoglobulin-associated protein; surface IgM-associated protein.
Gene ID
973
Accession Number
NP_001774.1NP_067612.1
Reactivity
Bovine|Chicken|Guinea Pig|Horse|Human|Mouse|Opossum|Porcine|Rabbit|Rat
Immunogen
Synthetic peptide corresponding to amino acids 202-216 of human CD79a
Target
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Clonality
Monoclonal
Clone
HM57
Conjugation
APC
Type
Monoclonal Antibody
Applications
Flow cytometry
Purification
Purified by size-exclusion chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
10 ul / test
Format
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
HLDA V; WS Code BC cB018 HLDA VI; WS Code BP 193 HLDA VI; WS Code BP 89 HLDA VI; WS Code B B103 HLDA VI; WS Code B CD79.4//
NCBI Gene Symbol
CD79A
Host or Source
Mouse
Protein Name
B-cell antigen receptor complex-associated protein alpha chain
Gene Name URL
CD79A
Nucleotide Accession Number
NM_001783.3NM_021601.3

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