CD55 Antibody

• Gene Name:

  CD55 molecule (Cromer blood group)

• Gene Aliases:

  CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group) ; CHAPLE; complement decay-accelerating factor; CR; CROM; Cromer blood group antigen; DAF; Rh blood group D antigen; TC.

• Gene ID:

  1604

• Accession Number:

  NP_000565.1NP_001108224.1NP_001287832.1NP_001287833.1

• Reactivity:

  Human|Non-human Primate

• Immunogen:

  HPB-ALL human T cell line

• Target:

  This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274) . Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829) .

• Clonality:

  Monoclonal

• Clone:

  MEM-118

• Conjugation:

  R-PE

• Type:

  Monoclonal Antibody

• Applications:

  Flow cytometry

• Purification:

  Purified by size-exclusion chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  10 ul / test

• Format:

  Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

• Buffer:

  The reagent is provided in Tris buffered saline (TBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

• Reconstitution:

  2°C to 8°C

• Fragment:

  IgM

• Specificity:

  HLDA V; WS Code AS S016//

• NCBI Gene Symbol:

  CD55

• Host or Source:

  Mouse

• Protein Name:

  Complement decay-accelerating factor

• Gene Name URL:

  CD55

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_000574.4NM_001114752.2NM_001300903.1NM_001300904.1