PTPRC Antibody

CAT: 0247-OAEE00872-100TSize: 100 TestsDry Ice: NoHazardous: No
CAT#:0247-OAEE00872-100TSize:100 Tests
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CAS Number
9007-83-4
Gene Name
Protein tyrosine phosphatase receptor type C
Gene Aliases
B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; Leukocyte common antigen; LY5; protein tyrosine phosphatase, receptor type, c polypeptide; receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen.
Gene ID
5788
Accession Number
NP_002829.3NP_563578.2
Reactivity
Human
Immunogen
Human thymocytes and T lymphocytes.
Target
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity) .
Clonality
Monoclonal
Clone
MEM-28
Conjugation
APC
Type
Monoclonal Antibody
Applications
Flow cytometry
Purification
Purified by size-exclusion chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
10 ul / test
Format
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
HLDA III; WS Code NL 833a//
NCBI Gene Symbol
PTPRC
Host or Source
Mouse
Protein Name
Receptor-type tyrosine-protein phosphatase C
Gene Name URL
PTPRC
Nucleotide Accession Number
NM_002838.4NM_080921.3

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