CD163 Antibody

CAT: 0247-OAEE00676-100TSize: 100 TestsDry Ice: NoHazardous: No
CAT#:0247-OAEE00676-100TSize:100 Tests
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
CD163 molecule
Gene Aliases
Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; SCARI1; scavenger receptor cysteine-rich type 1 protein M130.
Gene ID
9332
Accession Number
NP_004235.4NP_981961.2
Reactivity
Human
Immunogen
Hairy cell leukemia cells
Target
Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.
Clonality
Monoclonal
Clone
GHI/61
Conjugation
APC
Type
Monoclonal Antibody
Applications
Flow cytometry
Purification
Purified by size-exclusion chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
10 ul / test
Format
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
HLDA VI; WS Code M38 //
NCBI Gene Symbol
CD163
Host or Source
Mouse
Protein Name
Scavenger receptor cysteine-rich type 1 protein M130
Gene Name URL
CD163
Nucleotide Accession Number
NM_004244.5NM_203416.3

Related Products

CatalogName
OACA12705-100ULCD163 Recombinant Antibody [7B2] (OACA12705)
OPCD01986-200UGCD163 Recombinant Protein
OCOA01240-20UGCD163 Protein Lysate
OPCD01986-50UGCD163 Recombinant Protein
OPCD01986-10UGCD163 Recombinant Protein
OPCD01985-50UGCD163 Recombinant Protein
OPCD01985-200UGCD163 Recombinant Protein
OPCD01985-10UGCD163 Recombinant Protein
OPPA02272-10UGCD163 Porcine Protein
OAAV01081-200UGCD163 Recombinant Antibody [2A10 (2A10/11) ]

Alternative Products

CatalogName
V0017-01CD163 (ABT-CD163) Antibody
MBS9510622-01Anti-CD163 Antibody [ABT-CD163]
MBS8584457-01CD163 Antibody

Popular Products