SEMA7A Antibody

• Gene Name:

  Semaphorin 7A (John Milton Hagen blood group)

• Gene Aliases:

  CD108; CDw108; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group) ; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema K1; sema L; SEMAK1; SEMAL; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) ; semaphorin-7A; semaphorin-K1; semaphorin-L.

• Gene ID:

  8482

• Accession Number:

  NP_001139501.1NP_001139502.1NP_003603.1

• Reactivity:

  Human

• Immunogen:

  HPB-ALL human T cell line

• Target:

  Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

• Clonality:

  Monoclonal

• Clone:

  MEM-150

• Conjugation:

  FITC

• Type:

  Monoclonal Antibody

• Applications:

  Flow cytometry

• Purification:

  Purified by size-exclusion chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  20 ul / test

• Format:

  Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

• Buffer:

  The reagent is provided in Tris buffered saline (TBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

• Reconstitution:

  2°C to 8°C

• Fragment:

  IgM

• Specificity:

  HLDA V; WS Code AS S017 HLDA V; WS Code BP BP347 HLDA VI; WS Code BP 401 HLDA VI; WS Code BP 475 HLDA VI; WS Code NL N-L156 HLDA VI; WS Code P PR-65//

• NCBI Gene Symbol:

  SEMA7A

• Host or Source:

  Mouse

• Protein Name:

  Semaphorin-7A

• Gene Name URL:

  SEMA7A

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001146029.1NM_001146030.1NM_003612.3