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SOS1 Antibody

CAT: 0247-OAEE00533-100UGSize: 0.1 mg (C100)Dry Ice: NoHazardous: No
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CAT#:0247-OAEE00533-100UGSize:0.1 mg (C100)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
SOS Ras/Rac guanine nucleotide exchange factor 1
Gene Aliases
GF1; GGF1; GINGF; gingival fibromatosis, hereditary, 1; guanine nucleotide exchange factor; HGF; NS4; son of sevenless homolog 1; SOS-1.
Gene ID
6654
Accession Number
NP_005624.2
Reactivity
Human|Mouse|Non-human Primate
Immunogen
Peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human Sos protein.
Target
Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579) . Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331) . Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity) .
Clonality
Monoclonal
Clone
SOS-01
Type
Monoclonal Antibody
Applications
Immunocytochemistry|Western blot
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
The antibody SOS-01 reacts with human Sos, an ubiquitously expressed 150 kDa intracellular protein.
NCBI Gene Symbol
SOS1
Host or Source
Mouse
Protein Name
Son of sevenless homolog 1
Gene Name URL
SOS1
Nucleotide Accession Number
NM_005633.3

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