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SIT1 Antibody

CAT: 0247-OAEE00530-100UGSize: 0.1 mg (C100)Dry Ice: NoHazardous: No
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CAT#:0247-OAEE00530-100UGSize:0.1 mg (C100)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Signaling threshold regulating transmembrane adaptor 1
Gene Aliases
Gp30/40; SHP2 interacting transmembrane adaptor; SHP-2 interacting transmembrane adaptor protein; SHP2-interacting transmembrane adapter protein; SHP2-interacting transmembrane adaptor protein; signaling threshold-regulating transmembrane adapter 1; SIT; SIT-R; suppression inducing transmembrane adaptor 1; suppression-inducing transmembrane adapter 1.
Gene ID
27240
Accession Number
NP_055265.1
Reactivity
Human
Immunogen
Bacterially produced recombinant intracellular fragment of human SIT.
Target
Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells. Involved in positive selection of T-cells.
Clonality
Monoclonal
Clone
SIT-01
Type
Monoclonal Antibody
Applications
Flow cytometry|Immunoprecipitation|Western blot
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
The antibody SIT-01 reacts with SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs. It weakly crossreacts with mouse SIT.
NCBI Gene Symbol
SIT1
Host or Source
Mouse
Protein Name
Signaling threshold-regulating transmembrane adapter 1
Gene Name URL
SIT1
Nucleotide Accession Number
NM_014450.2

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