GB Antibody

CAT: 0247-OAEE00453-100UGSize: 0.1 mg (C100)Dry Ice: NoHazardous: No
CAT#:0247-OAEE00453-100UGSize:0.1 mg (C100)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Envelope glycoprotein B
Gene Aliases
Envelope glycoprotein B; HHV1gp00p48.
Gene ID
24271469
Reactivity
Herpes Simplex Virus
Immunogen
Exctract of HSV-1 infected VERO (green monkey kidney) cells.
Target
Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress (By similarity) . Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation) .
Clonality
Monoclonal
Clone
T111
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Reconstitution
2°C to 8°C
Fragment
IgG2b
Specificity
The antibody T111 recognizes gB antigen of both HSV1 and HSV2 (Herpes Simplex Virus type 1 and 2), a dsDNA virus, member of Herpesviridae family.
NCBI Gene Symbol
UL27
Host or Source
Mouse
Protein Name
Envelope glycoprotein B
Gene Name URL
UL27

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