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Chc Antibody

CAT: 0247-OAEE00351-100UGSize: 0.1 mg (C100)Dry Ice: NoHazardous: No
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CAT#:0247-OAEE00351-100UGSize:0.1 mg (C100)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Clathrin heavy chain
Gene Aliases
CHC; CHC17; clathrin heavy chain 1; clathrin heavy chain on chromosome 17; clathrin, heavy polypeptide (Hc) ; clathrin, heavy polypeptide-like 2; CLH-17; CLTCL2; Hc; MRD56.
Gene ID
1213
Accession Number
NP_001096993.1NP_001096994.1NP_001285300.1NP_477042.1NP_727901.1NP_996451.1NP_996452.1
Reactivity
Bovine|Human|Mouse|Porcine|Rat
Target
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed:15858577, PubMed:16968737, PubMed:21297582) . The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825) . Plays a role in early autophagosome formation (PubMed:20639872) .
Clonality
Monoclonal
Clone
BF-06
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunoprecipitation|Western blot
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Buffer
Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
Reconstitution
2°C to 8°C
Fragment
IgM
Specificity
The antibody BF-06 recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa protein involved in receptor-mediated endocytosis.
NCBI Gene Symbol
CLTC
Host or Source
Mouse
Protein Name
Clathrin heavy chain 1
Gene Name URL
CLTC
Nucleotide Accession Number
NM_001103523.2NM_001103524.2NM_001298371.1NM_057694.3NM_167466.2NM_206728.2NM_206729.2

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