CD55 Antibody

• Gene Name :

  CD55 molecule (Cromer blood group)

• Gene Aliases :

  CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group) ; CHAPLE; complement decay-accelerating factor; CR; CROM; Cromer blood group antigen; DAF; Rh blood group D antigen; TC.

• Gene ID :

  1604

• Accession Number :

  NP_000565.1NP_001108224.1NP_001287832.1NP_001287833.1

• Reactivity :

  Human|Non-human Primate

• Immunogen :

  HPB-ALL human T cell line

• Target :

  This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274) . Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829) .

• Clonality :

  Monoclonal

• Clone :

  MEM-118

• Type :

  Monoclonal Antibody

• Applications :

  Flow cytometry|Immunohistochemistry-Paraffin|Immunoprecipitation|Western blot

• Purification :

  Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Format :

  Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

• Buffer :

  Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0

• Reconstitution :

  2°C to 8°C

• Fragment :

  IgM

• Specificity :

  HLDA V; WS Code AS S016//

• NCBI Gene Symbol :

  CD55

• Host or Source :

  Mouse

• Protein Name :

  Complement decay-accelerating factor

• Gene Name URL :

  CD55

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_000574.4NM_001114752.2NM_001300903.1NM_001300904.1