CD300A Antibody

CAT: 0247-OAEE00198-100UGSize: 0.1 mg (C100)Dry Ice: NoHazardous: No
CAT#:0247-OAEE00198-100UGSize:0.1 mg (C100)
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CAS Number
9007-83-4
Gene Name
CD300a molecule
Gene Aliases
CD300 antigen-like family member A; CD300a antigen; CLM-8; CMRF35H; CMRF35-H; CMRF-35H; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35H9; CMRF35-H9; CMRF-35-H9; CMRF35-like molecule 8; IGSF12; immunoglobulin superfamily member 12; inhibitory receptor protein 60; IRC1; IRC1/IRC2; IRC2; IRp60; leukocyte membrane antigen; NK inhibitory receptor.
Gene ID
11314
Accession Number
NP_001243770.1NP_009192.2
Reactivity
Human
Immunogen
HPB human acute lymphoid leukemia cell line
Target
Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:10746781, PubMed:16339535, PubMed:9701027) . Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (PubMed:22043923) .
Clonality
Monoclonal
Clone
MEM-260
Type
Monoclonal Antibody
Applications
Flow cytometry|Western blot
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
The antibody MEM-260 reacts with CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25% of circulating T cells and 15% of circulating B cells.
NCBI Gene Symbol
CD300A
Host or Source
Mouse
Protein Name
CMRF35-like molecule 8
Gene Name URL
CD300A
Nucleotide Accession Number
NM_001256841.1NM_007261.3

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