ARAP1 Antibody

• Gene Name:

  ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

• Gene Aliases:

  Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1; centaurin-delta-2; CENTD2; cnt-d2.

• Gene ID:

  116985

• Accession Number:

  NP_001035207.1NP_001128662.1NP_056057.2

• Reactivity:

  Human

• Immunogen:

  His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1

• Target:

  Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns (3,4,5) P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns (3,4,5) P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity) .

• Clonality:

  Monoclonal

• Clone:

  ARAP1-2

• Type:

  Monoclonal Antibody

• Applications:

  Immunocytochemistry|Immunoprecipitation|Western blot

• Purification:

  Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• Buffer:

  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

• Reconstitution:

  2°C to 8°C

• Fragment:

  IgG1

• Specificity:

  The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein.

• NCBI Gene Symbol:

  ARAP1

• Host or Source:

  Mouse

• Protein Name:

  Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

• Gene Name URL:

  ARAP1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001040118.2NM_001135190.1NM_015242.4