PRF1 Antibody

• Gene Name:

  Perforin 1 (pore forming protein)

• Gene Aliases:

  Cytolysin; lymphocyte pore-forming protein; P; P1; pe; perforin-1; Pfn; Pfp; pore forming protein; Prf; Prf-1.

• Gene ID:

  18646

• Accession Number:

  NP_001076585.1NP_005032.2

• Reactivity:

  Human|Mouse

• Immunogen:

  Recombinant mouse perforin (aa 98-534) .

• Target:

  Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

• Clonality:

  Monoclonal

• Clone:

  CE2.10

• Type:

  Monoclonal Antibody

• Applications:

  Immunoprecipitation|Western blot

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1mg/ml

• Reconstitution:

  Long Term Storage : //+4C Handling : //Do not freeze/thaw. Stable for at least 6 months after receipt when stored undiluted at +4C.Handling : //Do not freeze/thaw. Stable for at least 6 months after receipt when stored undiluted at +4C.

• Fragment:

  IgG2a

• Specificity:

  Recognizes an epitope in the region aa 402-534 of human and mouse perforin.

• NCBI Gene Symbol:

  Prf1

• Host or Source:

  Mouse

• Protein Name:

  Perforin-1

• Gene Name URL:

  Prf1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001083116.1NM_005041.4