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PRF1 Antibody

CAT: 0247-OAED00295-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAED00295-100UGSize:100 µg
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CAS Number
9007-83-4
Gene Name
Perforin 1 (pore forming protein)
Gene Aliases
Cytolysin; lymphocyte pore-forming protein; P; P1; pe; perforin-1; Pfn; Pfp; pore forming protein; Prf; Prf-1.
Gene ID
18646
Reactivity
Mouse
Immunogen
Recombinant mouse perforin (aa 98-534)
Target
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Clonality
Monoclonal
Clone
CB5.4
Type
Monoclonal Antibody
Source
Purified from mouse ascites
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid.// In PBS containing 0.02% sodium azide
Reconstitution
For short-term storage, store at 4° C; for long-term storage, store at -20° C. Stable for at least 6 months after receipt when stored at 4° C. Avoid freeze/thaw cycles. _x005F _x005F _x005F
Fragment
IgG2a
Specificity
Recognizes an epitope in the region aa 402-534
NCBI Gene Symbol
Prf1
Host or Source
Rat
Protein Name
Perforin-1
Gene Name URL
Prf1

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