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EXOC3 Antibody

CAT: 0247-OAED00238-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OAED00238-50UGSize:50 µg
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CAS Number
9007-83-4
Gene Name
Exocyst complex component 3
Gene Aliases
SEC6, Sec6p, SEC6L1
Gene ID
11336
Accession Number
NP_009208.2
Reactivity
Human, Mouse, Rat, Bovine, Dog, Chicken, Hamster, Monkey, Pig, Rabbit, Sheep
Immunogen
Recombinant rat Sec6.
Target
RSec6 and rSec8 are rat homologs of the yeast Sec6 and Sec8 proteins that are essential for protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec8 is part of a 19.5S complex that includes Sec6 and Sec15, that also associate with the ras-like GTP binding protein Sec4. An analogous 17S complex in rat brain was found to contain rSec6 and rSec8, along with eight proteins with a combined molecular weight of 743 kDa. The membrane-associated rSec6/8 complex co-immunoprecipitates with syntaxin, providing evidence that this complex is involved in synaptic vesicle docking and fusion at the presynaptic terminal.
Clonality
Monoclonal
Clone
9H5
Type
Monoclonal Antibody
Applications
ICC, IHC, WB
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Reconstitution
Long Term Storage : //-20C
Fragment
IgG2a
Specificity
Recognizes human, mouse, rat, bovine, dog, chicken, hamster, monkey, pig, rabbit and sheep rSec6. Detects a band of ~87kDa by Western blot.
NCBI Gene Symbol
EXOC3
Host or Source
Mouse
Protein Name
Exocyst complex component 3
Gene Name URL
EXOC3
Nucleotide Accession Number
NM_007277.4

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