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TNF-alpha Antibody

CAT: 0247-OADB00425-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OADB00425-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Tumor necrosis factor
Gene Aliases
DIF, TNFA, TNFSF2, TNLG1F, TNF-alpha
Gene ID
7124
Accession Number
NP_000585.2
Reactivity
Human
Target
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Clonality
Monoclonal
Clone
B-C7
Type
Monoclonal Antibody
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.1 mg/ml
Bioactivity
This Antibody can be used as Detection in a human TNF-a sandwich Immunoassay to detect human TNF-a in combination with human TNF-a Capture Antibody
Format
Lyophilized
Buffer
Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*.
Reconstitution
Store at +2-8C for 12 months
Molecular Weight
26 kDa
Fragment
Mouse IgG1
Specificity
Recognises both natural and recombinant TNF-a
NCBI Gene Symbol
TNF-alpha
Host or Source
Mouse
Protein Name
Tumor necrosis factor
Gene Name URL
TNF-alpha
Nucleotide Accession Number
NM_000594.3

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