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IL-27 Antibody

CAT: 0247-OADB00357-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OADB00357-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Interleukin 27
Gene Aliases
P28, IL30, IL-27, IL27A, IL-27A, IL27p28
Gene ID
246778
Accession Number
NP_663634.2
Reactivity
Human
Target
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) .
Clonality
Monoclonal
Clone
B-G49
Type
Monoclonal Antibody
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.1 mg/ml
Bioactivity
This Antibody can be used as Detection in a human IL-27 sandwich Immunoassay to detect human IL-27 in combination with human IL-27 Capture Antibody
Format
Lyophilized
Buffer
Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*.
Reconstitution
Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C
Molecular Weight
27 kDa
Fragment
Mouse IgG2a
Specificity
Recognises both natural and recombinant IL-27
NCBI Gene Symbol
IL-27
Host or Source
Mouse
Protein Name
Interleukin-27 subunit alpha
Gene Name URL
IL-27
Nucleotide Accession Number
NM_145659.3