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IL-23 Antibody

CAT: 0247-OADB00350-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OADB00350-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Interleukin 23 subunit alpha
Gene Aliases
P19, SGRF, IL-23, IL-23A, IL23P19
Gene ID
51561
Accession Number
NP_057668.1
Reactivity
Human
Target
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23) . IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B) . The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG) . In contrast to IL12, which acts mainly on naive CD4 (+) T cells, IL23 preferentially acts on memory CD4 (+) T cells.
Clonality
Monoclonal
Clone
B-F43
Type
Monoclonal Antibody
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.1 mg/ml
Bioactivity
This Antibody can be used as Detection in a human IL-23 sandwich Immunoassay to detect human IL-23 in combination with human IL-23 Capture Antibody
Format
Lyophilized
Buffer
Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*.
Reconstitution
Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C
Molecular Weight
21 kDa
Fragment
Mouse IgG1
Specificity
Recognises both natural and recombinant IL-23, p19 sub-unit
NCBI Gene Symbol
IL-23
Host or Source
Mouse
Protein Name
Interleukin-23 subunit alpha
Gene Name URL
IL-23
Nucleotide Accession Number
NM_016584.2

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