CD86 Antibody

CAT: 0247-OADB00266-2MLSize: 2 mLDry Ice: NoHazardous: No
CAT#:0247-OADB00266-2MLSize:2 mL
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CAS Number
9007-83-4
Gene Name
CD86 molecule
Gene Aliases
B70, B7-2, B7.2, LAB72, CD28LG2
Gene ID
942
Accession Number
NP_001193853.1
Reactivity
Human
Target
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Clonality
Monoclonal
Clone
B-T7
Type
Monoclonal Antibody
Applications
FC
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 tests/2mL
Format
Liquid
Buffer
Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide
Reconstitution
Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Molecular Weight
38 kDa
Fragment
Mouse IgG1
Specificity
Recognises the B7.2, B70 antigen, a 80 kDa protein
NCBI Gene Symbol
CD86
Host or Source
Human
Protein Name
T-lymphocyte activation antigen CD86
Gene Name URL
CD86
Nucleotide Accession Number
NM_001206924.1

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