CD8 Antibody

• Gene Name :

  CD8a molecule

• Gene Aliases :

  CD8, p32, Leu2

• Gene ID :

  925

• Accession Number :

  NP_001139345.1

• Reactivity :

  Human

• Target :

  The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

• Clonality :

  Monoclonal

• Clone :

  B-Z31

• Type :

  Monoclonal Antibody

• Applications :

  IHC

• Purification :

  Affinity chromatography on Protein A

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 ug/uL

• Format :

  Liquid

• Buffer :

  Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

• Reconstitution :

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight :

  26 kDa

• Fragment :

  Mouse IgG2a

• Specificity :

  Recognises the T-cell coreceptor, a 32-34 kDa protein

• NCBI Gene Symbol :

  CD8

• Host or Source :

  Mouse

• Protein Name :

  T-cell surface glycoprotein CD8 alpha chain

• Gene Name URL :

  CD8

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001145873.1