CD202b Antibody

• Gene Name:

  TEK receptor tyrosine kinase

• Gene Aliases:

  TIE2, VMCM, GLC3E, TIE-2, VMCM1, CD202B

• Gene ID:

  7010

• Accession Number:

  NP_000450.2

• Reactivity:

  Human

• Target:

  This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF) -like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

• Clonality:

  Monoclonal

• Clone:

  B-B48

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Purification:

  Ion exchange chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  200 tests/2mL

• Format:

  Lyophilized

• Buffer:

  Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide

• Reconstitution:

  Stable at +2-8C for 12 months. For longer storage freeze aliquots.

• Molecular Weight:

  126 kDa

• Fragment:

  IgG1

• Specificity:

  Recognises Tie2, Tek, an unknown kDa protein

• NCBI Gene Symbol:

  CD202b

• Host or Source:

  Mouse

• Protein Name:

  Angiopoietin-1 receptor

• Gene Name URL:

  CD202b

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_000459.4