CD1b/c Antibody

• Gene Name:

  CD1b molecule; CD1c molecule

• Gene Aliases:

  R1, CD1, CD1A

• Gene ID:

  910; 911

• Accession Number:

  NP_001755.1

• Reactivity:

  Human

• Target:

  This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

• Clonality:

  Monoclonal

• Clone:

  B-B5

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Purification:

  Ion exchange chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  200 tests/2mL

• Format:

  Lyophilized

• Buffer:

  Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide

• Reconstitution:

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight:

  37kDa, 38 kDa

• Fragment:

  IgG1

• Specificity:

  Recognises a 43-45 kDa protein

• NCBI Gene Symbol:

  CD1b/c

• Host or Source:

  Mouse

• Protein Name:

  T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1c

• Gene Name URL:

  CD1b/c

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001764.2