CD178 Antibody

• Gene Name :

  Fas ligand

• Gene Aliases :

  APTL, FASL, CD178, CD95L, ALPS1B, CD95-L, TNFSF6, TNLG1A, APT1LG1

• Gene ID :

  356

• Accession Number :

  NP_000630.1

• Reactivity :

  Human

• Target :

  This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE) . Alternatively spliced transcript variants have been described.

• Clonality :

  Monoclonal

• Clone :

  B-R17

• Type :

  Monoclonal Antibody

• Applications :

  FC

• Purification :

  Ion exchange chromatography

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  200 tests/2mL

• Format :

  Lyophilized

• Buffer :

  Phosphate-buffered saline with 1 % BSA and 0.1 % sodium azide

• Reconstitution :

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight :

  31 kDa

• Fragment :

  IgG1

• Specificity :

  Recognises APO1L, Fas ligand (FAS L), a 40 kDa protein

• NCBI Gene Symbol :

  CD178

• Host or Source :

  Mouse

• Protein Name :

  Tumor necrosis factor ligand superfamily member 6

• Gene Name URL :

  CD178

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_000639.2