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CD11a Antibody

CAT: 0247-OADB00034-2MLSize: 2 mLDry Ice: NoHazardous: No
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CAT#:0247-OADB00034-2MLSize:2 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Integrin subunit alpha L
Gene Aliases
CD11A, LFA-1, LFA1A
Gene ID
3683
Accession Number
NP_001107852.1
Reactivity
Human
Target
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Clonality
Monoclonal
Clone
B-B15
Type
Monoclonal Antibody
Applications
FC
Purification
Affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 tests/2mL
Format
Lyophilized
Buffer
Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide
Reconstitution
Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Molecular Weight
129 kDa
Fragment
IgG1
Specificity
Recognises the αL integrin of LFA-1 complex, a 180 kDa protein
NCBI Gene Symbol
CD11a
Host or Source
Mouse
Protein Name
Integrin alpha-L
Gene Name URL
CD11a
Nucleotide Accession Number
NM_001114380.1

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