CD11a Antibody

• Gene Name:

  Integrin subunit alpha L

• Gene Aliases:

  CD11A, LFA-1, LFA1A

• Gene ID:

  3683

• Accession Number:

  NP_001107852.1

• Reactivity:

  Human

• Target:

  ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

• Clonality:

  Monoclonal

• Clone:

  B-B15

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Purification:

  Affinity chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 ug/uL

• Format:

  Lyophilized

• Buffer:

  Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

• Reconstitution:

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight:

  129 kDa

• Fragment:

  IgG1

• Specificity:

  Recognises the αL integrin of LFA-1 complex, a 180 kDa protein

• NCBI Gene Symbol:

  CD11a

• Host or Source:

  Mouse

• Protein Name:

  Integrin alpha-L

• Gene Name URL:

  CD11a

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001114380.1