CD117 Antibody

• Gene Name:

  KIT proto-oncogene receptor tyrosine kinase

• Gene Aliases:

  PBT, SCFR, C-Kit, CD117, MASTC

• Gene ID:

  3815

• Accession Number:

  NP_000213.1

• Reactivity:

  Human

• Target:

  This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

• Clonality:

  Monoclonal

• Clone:

  B-K15

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Purification:

  Ion exchange chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  200 tests/2mL

• Format:

  Lyophilized

• Buffer:

  Phosphate-buffered saline with 1 % BSA and 0.1 % sodium azide

• Reconstitution:

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight:

  110 kDa

• Fragment:

  IgG1

• Specificity:

  Recognises the Stem Cell Factor Receptor, SCF R, c-kit, a 145 kDa protein

• NCBI Gene Symbol:

  CD117

• Host or Source:

  Mouse

• Protein Name:

  Mast/stem cell growth factor receptor Kit

• Gene Name URL:

  CD117

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_000222.2