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KMT5C Antibody

CAT: 0247-OACD07567-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACD07567-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Lysine methyltransferase 5C
Gene Aliases
[histone H4]-lysine20 N-methyltransferase KMT5B; [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; BC024816; histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; lysine-specific methyltransferase 5C; su (var) 4-20 homolog 2; suppressor of variegation 4-20 homolog 2; Suv420; Suv4-20; Suv420h2; Suv4-20h2.
Gene ID
232811
Accession Number
NP_001108490.1
Reactivity
Mouse|Rat
Immunogen
Range: Gly2 - Leu279
Target
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
53 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against SUV420H2. It has been selected for its ability to recognize SUV420H2 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Kmt5c
Host or Source
Rabbit
Protein Name
Histone-lysine N-methyltransferase KMT5C
Gene Name URL
Kmt5c
Nucleotide Accession Number
NM_001115018

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