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RAPGEF1 Antibody

CAT: 0247-OACD06914-1MLSize: 1 mLDry Ice: NoHazardous: No
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CAT#:0247-OACD06914-1MLSize:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Rap guanine nucleotide exchange factor 1
Gene Aliases
C3G; CRK SH3-binding GNRP; GRF2; Guanine nucleotide-releasing factor 2; guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene) ; Protein C3G; Rap guanine nucleotide exchange factor (GEF) 1; rap guanine nucleotide exchange factor 1.
Gene ID
2889
Accession Number
NP_001291204.1
Reactivity
Human|Mouse|Rat
Immunogen
Range: Lys780 - Asn1035
Target
Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF) -induced sustained activation of Rap1 and neurite outgrowth.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
116 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against RAPGEF1. It has been selected for its ability to recognize RAPGEF1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
RAPGEF1
Host or Source
Rabbit
Protein Name
Rap guanine nucleotide exchange factor 1
Gene Name URL
RAPGEF1
Nucleotide Accession Number
NM_001304275

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