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RFTN1 Antibody

CAT: 0247-OACD06890-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACD06890-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Raftlin lipid raft linker 1
Gene Aliases
2310015N21Rik; AI853526; raftlin; raft-linking protein.
Gene ID
76438
Accession Number
NP_852062.1
Reactivity
Mouse
Immunogen
Range: Ala207 - Phe451
Target
Involved in protein trafficking via association with clathrin and AP2 complex (By similarity) . Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly (I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195) . Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (PubMed:19414744) . May regulate B-cell antigen receptor-mediated signaling (By similarity) . May play a pivotal role in the formation and/or maintenance of lipid rafts (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.51 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
62 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against Raftlin. It has been selected for its ability to recognize Raftlin in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Rftn1
Host or Source
Rabbit
Protein Name
Raftlin
Gene Name URL
Rftn1
Nucleotide Accession Number
NM_181397

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