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PZP Antibody

CAT: 0247-OACD06873-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACD06873-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Pregnancy-zone protein
Gene Aliases
A1m; alpha-1-M; alpha-1-macroglobulin; alpha-1-macroglobulin 165 kDa subunit.
Gene ID
252922
Accession Number
NP_665722.2
Reactivity
Rat
Immunogen
Range: Leu1251 - Ala1500
Target
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced) . Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunohistochemistry|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
167 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against PZP. It has been selected for its ability to recognize PZP in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Pzp
Host or Source
Rabbit
Protein Name
Alpha-1-macroglobulin
Gene Name URL
Pzp
Nucleotide Accession Number
NM_145779