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PPIE Antibody

CAT: 0247-OACD06659-1MLSize: 1 mLDry Ice: NoHazardous: No
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CAT#:0247-OACD06659-1MLSize:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Peptidylprolyl isomerase E
Gene Aliases
Cyclophilin E; cyclophilin-33; CYP33; CYP-33; peptidyl-prolyl cis-trans isomerase E; peptidylprolyl isomerase E (cyclophilin E) ; PPIase E; rotamase E.
Gene ID
10450
Accession Number
NP_001181936.1
Reactivity
Human|Mouse|Rat
Immunogen
Range: Tyr41 - Val264
Target
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346) . Combines RNA-binding and PPIase activities (PubMed:8977107, PubMed:18258190, PubMed:20677832, PubMed:20460131) . Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly (A) -region in the 3'-UTR of mRNA molecules (PubMed:8977107, PubMed:18258190, PubMed:20460131) . Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins (PubMed:8977107, PubMed:18258190, PubMed:20677832, PubMed:20541251) . Inhibits KMT2A activity; this requires proline isomerase activity (PubMed:20677832, PubMed:20541251, PubMed:20460131) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
33 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against PPIE. It has been selected for its ability to recognize PPIE in immunohistochemical staining and western blotting.
NCBI Gene Symbol
PPIE
Host or Source
Rabbit
Protein Name
Peptidyl-prolyl cis-trans isomerase E
Gene Name URL
PPIE
Nucleotide Accession Number
NM_001195007