PLAA Antibody

• Gene Name :

  Phospholipase A2 activating protein

• Gene Aliases :

  DOA1; DOA1 homolog; NDMSBA; phospholipase A-2-activating protein; PLA2P; PLAP.

• Gene ID :

  9373

• Accession Number :

  NP_001026859.1

• Reactivity :

  Human|Mouse|Rat

• Immunogen :

  Range: Trp367 - Ser468

• Target :

  Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (PubMed:27753622) . Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (By similarity) . May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622) . Plays a role in cerebellar Purkinje cell development (By similarity) . Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha) - or lipopolysaccharide (LPS) -dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:18291623, PubMed:28007986) .

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification :

  Affinity Purified; Protein A Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.5 mg/ml

• Format :

  Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

• Reconstitution :

  2°C to 8°C|-20°C

• Molecular Weight :

  87 kDa

• Fragment :

  IgG

• Specificity :

  The antibody is a rabbit polyclonal antibody raised against PLAA. It has been selected for its ability to recognize PLAA in immunohistochemical staining and western blotting.

• NCBI Gene Symbol :

  PLAA

• Host or Source :

  Rabbit

• Protein Name :

  Phospholipase A-2-activating protein

• Gene Name URL :

  PLAA

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001031689