Products for Research Use Only
RegisterLogin

CD274 Antibody

CAT: 0247-OACD06351-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACD06351-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
CD274 antigen
Gene Aliases
A530045L16Rik; B7 homolog 1; B7h1; PD-; PDCD1 ligand 1; Pdcd1l; Pdcd1l1; Pdcd1lg1; Pdl1; programmed cell death 1 ligand 1.
Gene ID
60533
Accession Number
NP_068693.1
Reactivity
Mouse
Immunogen
Recombinant PDL (Leu48 - Thr290) expressed in E.coli
Target
Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11238124) . The PDCD1-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (By similarity) . May costimulate helper T-cell subsets through a yet unknown activating receptor (PubMed:11015443, PubMed:12719480) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against PDCD1LG1. It has been selected for its ability to recognize PDCD1LG1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Cd274
Host or Source
Rabbit
Protein Name
Programmed cell death 1 ligand 1
Gene Name URL
Cd274
Nucleotide Accession Number
NM_021893

Related Products

CatalogName
OPCD06041-10UGCD274 Recombinant Protein
OPCD06040-50UGCD274 Recombinant Protein
OPCD06041-200UGCD274 Recombinant Protein
OPCD06039-10UGCD274 Recombinant Protein
OPCD06042-200UGCD274 Recombinant Protein
OPCD06039-50UGCD274 Recombinant Protein
OPCD06039-200UGCD274 Recombinant Protein
OPCD06040-200UGCD274 Recombinant Protein
OPCD06040-10UGCD274 Recombinant Protein
OPCD06042-10UGCD274 Recombinant Protein

Alternative Products

CatalogName
GWB-54C64BCD274 Antibody

Popular Products