MAP3K1 Antibody

• Gene Name:

  Mitogen-activated protein kinase kinase kinase 1

• Gene Aliases:

  MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MAPKKK1; MEK kinase 1; MEKK; MEKK 1; MEKK1; mitogen-activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; SRXY6.

• Gene ID:

  4214

• Accession Number:

  NP_005912.1

• Reactivity:

  Human|Mouse

• Immunogen:

  Range: Ile1307 - Arg1509

• Target:

  Component of a protein kinase signal transduction cascade (PubMed:9808624) . Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624) . May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173) . Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624) .

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  164 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against MAP3K1. It has been selected for its ability to recognize MAP3K1 in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  MAP3K1

• Host or Source:

  Rabbit

• Protein Name:

  Mitogen-activated protein kinase kinase kinase 1

• Gene Name URL:

  MAP3K1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_005921