ITGAE Antibody

• Gene Name:

  Integrin alpha E, epithelial-associated

• Gene Aliases:

  A530055J10; alph; alpha-E1; alpha-M290; aM290; CD103; integrin alpha M290; integrin alpha-E.

• Gene ID:

  16407

• Accession Number:

  NP_032425.2

• Reactivity:

  Mouse|Rat

• Immunogen:

  Recombinant ITGaE (Val671~Gln917) expressed in E.coli

• Target:

  Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against ITGaE. It has been selected for its ability to recognize ITGaE in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  Itgae

• Host or Source:

  Rabbit

• Protein Name:

  Integrin alpha-E

• Gene Name URL:

  Itgae

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_008399