IL37 Antibody

• Gene Name:

  Interleukin 37

• Gene Aliases:

  FIL1; FIL1 zeta; FIL1 (ZETA) ; FIL1Z; IL-1 zeta; IL1F7; IL-1F7; IL1F7 (canonical product IL-1F7b) ; IL-1F7b (IL-1H4, IL-1H, IL-1RP1) ; IL-1H; IL1H4; IL-1H4; IL1RP1; IL-1RP1; IL-1X; IL-1X protein; IL-23; IL-37; interleukin 1 family member 7; interleukin 1, zeta; Interleukin-1 family member 7; interleukin-1 homolog 4; interleukin-1 superfamily z; Interleukin-1 zeta; interleukin-1-related protein; interleukin-23; interleukin-37.

• Gene ID:

  27178

• Accession Number:

  NP_055254.2

• Reactivity:

  Human

• Immunogen:

  Range: Val46 - Asp218

• Target:

  Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  17 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against IL1z. It has been selected for its ability to recognize IL1z in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  IL37

• Host or Source:

  Rabbit

• Protein Name:

  Interleukin-37

• Gene Name URL:

  IL37

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_014439