IL1RN Antibody

CAT: 0247-OACD04665-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OACD04665-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
Interleukin 1 receptor antagonist
Gene Aliases
DIRA; ICIL-1RA; IL1 inhibitor; IL1F3; IL-1ra; IL1RA; IL-1ra3; IL-1RN; interleukin-1 receptor antagonist protein; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra) ; IRAP; MVCD4; type II interleukin-1 receptor antagonist.
Gene ID
3557
Accession Number
NP_000568.1
Reactivity
Human|Porcine
Immunogen
Range: Arg26 - Glu177
Target
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
16 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against IL1RA. It has been selected for its ability to recognize IL1RA in immunohistochemical staining and western blotting.
NCBI Gene Symbol
IL1RN
Host or Source
Rabbit
Protein Name
Interleukin-1 receptor antagonist protein
Gene Name URL
IL1RN
Nucleotide Accession Number
NM_000577

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