CD101 Antibody

• Gene Name:

  CD101 molecule

• Gene Aliases:

  Cell surface glycoprotein V7; EWI-101; glu-Trp-Ile EWI motif-containing protein 101; IGSF2; immunoglobulin superfamily member 2; leukocyte surface protein; V7.

• Gene ID:

  9398

• Accession Number:

  NP_001243035.1

• Reactivity:

  Human|Porcine

• Immunogen:

  Range: Ala566 - Leu784

• Target:

  Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4 (+) CD56 (+) leukemic tumor cells.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Immunohistochemistry|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  115 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against IGSF2. It has been selected for its ability to recognize IGSF2 in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  CD101

• Host or Source:

  Rabbit

• Protein Name:

  Immunoglobulin superfamily member 2

• Gene Name URL:

  CD101

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001256106