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CD79A Antibody

CAT: 0247-OACD04473-1MLSize: 1 mLDry Ice: NoHazardous: No
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CAT#:0247-OACD04473-1MLSize:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
CD79a molecule
Gene Aliases
B-cell antigen receptor complex-associated protein alpha chain; CD79a antigen (immunoglobulin-associated alpha) ; CD79a molecule, immunoglobulin-associated alpha; IGA; ig-alpha; MB-1; MB-1 membrane glycoprotein; membrane-bound immunoglobulin-associated protein; surface IgM-associated protein.
Gene ID
973
Accession Number
NP_001774.1
Reactivity
Human
Immunogen
Range: His36 - Gly219
Target
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Flow cytometry|Immunohistochemistry|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
21 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against Iga. It has been selected for its ability to recognize Iga in immunohistochemical staining and western blotting.
NCBI Gene Symbol
CD79A
Host or Source
Rabbit
Protein Name
B-cell antigen receptor complex-associated protein alpha chain
Gene Name URL
CD79A
Nucleotide Accession Number
NM_001783

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