RegisterLogin

DTX1 Antibody

CAT: 0247-OACD03126-1MLSize: 1 mLDry Ice: NoHazardous: No
CAT#:0247-OACD03126-1MLSize:1 mL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
Deltex E3 ubiquitin ligase 1
Gene Aliases
Deltex 1, E3 ubiquitin ligase; deltex homolog 1; E3 ubiquitin-protein ligase DTX1; hDx-1; protein deltex-1; RING-type E3 ubiquitin transferase DTX1; RNF140.
Gene ID
1840
Accession Number
NP_004407.2
Reactivity
Human|Mouse|Porcine|Rat
Immunogen
Range: Gly290 - His535
Target
Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity) . Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
67 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against DTX1. It has been selected for its ability to recognize DTX1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
DTX1
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase DTX1
Gene Name URL
DTX1
Nucleotide Accession Number
NM_004416

Related Products

CatalogName
OPCD02814-200UGDTX1 Recombinant Protein
OPCD02814-10UGDTX1 Recombinant Protein
OPCD02814-50UGDTX1 Recombinant Protein
OKEH01661-96WDTX1 ELISA Kit (Human)
OKEH05156-96WDTX1 ELISA Kit (Mouse)
OKEH01661DTX1 ELISA Kit (Human) (OKEH01661)
OKEH05156DTX1 ELISA Kit (Mouse) (OKEH05156)
AAP38458-100UGDTX1 Peptide - N-terminal region (AAP38458)
OACA08307-100ULDTX2 Antibody
OACA08308-50ULDTX2 Antibody

Alternative Products

CatalogName
MBS7127064-01DTX1 Antibody

Popular Products