TSC22D3 Antibody

• CAS Number :

  9007-83-4

• Gene Name :

  TSC22 domain family, member 3

• Gene Aliases :

  Delta sleep inducing peptide, immunoreactor; DIP; Ds; Dsip1; Gi; Gilz; glucocorticoid-induced leucine zipper protein; long glucocorticoid-induced leucine zipper protein; Tilz3; TSC22 domain family protein 3; TSC-22R; TSC22-related inducible leucine zipper 3; TSC22-related-inducible leucine zipper 3.

• Gene ID :

  14605

• Accession Number :

  NP_001070832.1

• Reactivity :

  Human|Mouse

• Immunogen :

  Range: Met1 - Val137

• Target :

  Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity) . Isoform 1 and isoform 4 inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification :

  Affinity Purified; Protein A Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.5 mg/ml

• Format :

  Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

• Reconstitution :

  2°C to 8°C|-20°C

• Molecular Weight :

  9 kDa

• Fragment :

  IgG

• Specificity :

  The antibody is a rabbit polyclonal antibody raised against dSIP. It has been selected for its ability to recognize dSIP in immunohistochemical staining and western blotting.

• NCBI Gene Symbol :

  Tsc22d3

• Host or Source :

  Rabbit

• Protein Name :

  TSC22 domain family protein 3

• Gene Name URL :

  Tsc22d3

• Nucleotide Accession Number :

  NM_001077364