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TSC22D3 Antibody

CAT: 0247-OACD03121-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACD03121-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
TSC22 domain family, member 3
Gene Aliases
Delta sleep inducing peptide, immunoreactor; DIP; Ds; Dsip1; Gi; Gilz; glucocorticoid-induced leucine zipper protein; long glucocorticoid-induced leucine zipper protein; Tilz3; TSC22 domain family protein 3; TSC-22R; TSC22-related inducible leucine zipper 3; TSC22-related-inducible leucine zipper 3.
Gene ID
14605
Accession Number
NP_001070832.1
Reactivity
Human|Mouse
Immunogen
Range: Met1 - Val137
Target
Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity) . Isoform 1 and isoform 4 inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
9 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against dSIP. It has been selected for its ability to recognize dSIP in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Tsc22d3
Host or Source
Rabbit
Protein Name
TSC22 domain family protein 3
Gene Name URL
Tsc22d3
Nucleotide Accession Number
NM_001077364

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