CFL2 Antibody

• Gene Name:

  Cofilin 2

• Gene Aliases:

  Cofilin 2 (muscle) ; Cofilin, muscle isoform; cofilin-2; NEM7; nemaline myopathy type 7.

• Gene ID:

  1073

• Accession Number:

  NP_001230574.1

• Reactivity:

  Human|Mouse|Porcine

• Immunogen:

  Range: Met1 - Asn156

• Target:

  Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3 (PubMed:19752190) . It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity) .

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunohistochemistry|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  17 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against CFL2. It has been selected for its ability to recognize CFL2 in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  CFL2

• Host or Source:

  Rabbit

• Protein Name:

  Cofilin-2

• Gene Name URL:

  CFL2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001243645