CD163 Antibody

• Gene Name :

  CD163 antigen

• Gene Aliases :

  CD163v2; CD163v3; scavenger receptor cysteine-rich type 1 protein M130.

• Gene ID :

  93671

• Accession Number :

  NP_444324.2

• Reactivity :

  Mouse

• Immunogen :

  Rrecombinant CD163 (Pro697 - Gly972) expressed in E.coli

• Target :

  Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity) .

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification :

  Affinity Purified; Protein A Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.5 mg/ml

• Format :

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution :

  2°C to 8°C|-20°C

• Fragment :

  IgG

• Specificity :

  The antibody is a rabbit polyclonal antibody raised against CD163. It has been selected for its ability to recognize CD163 in immunohistochemical staining and western blotting.

• NCBI Gene Symbol :

  Cd163

• Host or Source :

  Rabbit

• Protein Name :

  Scavenger receptor cysteine-rich type 1 protein M130

• Gene Name URL :

  Cd163

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_053094