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BMP2 Antibody

CAT: 0247-OACD01976-1MLSize: 1 mLDry Ice: NoHazardous: No
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CAT#:0247-OACD01976-1MLSize:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Bone morphogenetic protein 2
Gene Aliases
BDA2; BMP2A; bone morphogenetic protein 2; bone morphogenetic protein 2A; SSFSC; SSFSC1.
Gene ID
650
Accession Number
NP_001191.1
Reactivity
Human
Immunogen
Range: Gln283 - Arg396
Target
Induces cartilage and bone formation (PubMed:3201241) . Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.73 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
45 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against BMP2. It has been selected for its ability to recognize BMP2 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
BMP2
Host or Source
Rabbit
Protein Name
Bone morphogenetic protein 2
Gene Name URL
BMP2
Nucleotide Accession Number
NM_001200

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