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AGRP Antibody

CAT: 0247-OACD01510-1MLSize: 1 mLDry Ice: NoHazardous: No
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CAT#:0247-OACD01510-1MLSize:1 mL
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CAS Number
9007-83-4
Gene Name
Agouti related neuropeptide
Gene Aliases
Agouti related protein homolog; agouti-related protein; AGRT; ART; ASIP2.
Gene ID
181
Accession Number
NP_001129.1
Reactivity
Human
Immunogen
Recombinant AGRP (Gly20~Ser130) expressed in E.coli.
Target
Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity) . Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunohistochemistry|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
14 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against AGRP. It has been selected for its ability to recognize AGRP in immunohistochemical staining and western blotting.
NCBI Gene Symbol
AGRP
Host or Source
Rabbit
Protein Name
Agouti-related protein
Gene Name URL
AGRP
Nucleotide Accession Number
NM_001138

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