DNAJC2 Antibody

• Gene Name:

  DnaJ heat shock protein family (Hsp40) member C2

• Gene Aliases:

  AU020218; DnaJ (Hsp40) homolog, subfamily C, member 2; dnaJ homolog subfamily C member 2; Id associate 1; MID; MIDA1; Mouse Id associate 1; Zrf; Zrf1; Zrf2; zuotin related factor 2; zuotin-related factor 1.

• Gene ID:

  22791

• Accession Number:

  NP_033610.1

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  Range: Asp368 - Lys621

• Target:

  Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation (By similarity) . Specifically binds DNA sequence 5'-GTCAAGC-3'.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  72 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against ZRF1. It has been selected for its ability to recognize ZRF1 in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  Dnajc2

• Host or Source:

  Rabbit

• Protein Name:

  DnaJ homolog subfamily C member 2

• Gene Name URL:

  Dnajc2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_009584