CPLX1 Antibody

• Gene Name:

  Complexin 1

• Gene Aliases:

  Complexin I; complexin-1; CPX I; CPX1; CPX-I; DEE63; EIEE63; synaphin 2; Synaphin-2.

• Gene ID:

  10815

• Accession Number:

  NP_006642.1

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  Range: Met1 - Lys134

• Target:

  Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:21785414) . Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse (PubMed:21785414) . Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  15 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against CPLX1. It has been selected for its ability to recognize CPLX1 in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  CPLX1

• Host or Source:

  Rabbit

• Protein Name:

  Complexin-1

• Gene Name URL:

  CPLX1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_006651