GDF11 Antibody

• Gene Name :

  Growth differentiation factor 11

• Gene Aliases :

  BMP11; BMP-11; bone morphogenetic protein 11; GDF-11; growth/differentiation factor 11; VHO.

• Gene ID :

  10220

• Accession Number :

  NP_005802.1

• Reactivity :

  Human|Rat

• Immunogen :

  Recombinant GDF11 (Thr138~Asn386) expressed in E.coli.

• Target :

  Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity) . Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634) .

• Clonality :

  Monoclonal

• Clone :

  C4

• Type :

  Monoclonal Antibody

• Applications :

  Western blot

• Purification :

  Protein A/G Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Format :

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution :

  2°C to 8°C|-20°C

• Fragment :

  IgG2b Kappa

• Specificity :

  The antibody is a mouse monoclonal antibody raised against GDF11. It has been selected for its ability to recognize GDF11 in immunohistochemical staining and western blotting.

• NCBI Gene Symbol :

  GDF11

• Host or Source :

  Mouse

• Protein Name :

  Growth/differentiation factor 11

• Gene Name URL :

  GDF11

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_005811.3